ST. PAUL—Minnesota, like most states, is facing an opioid crisis. In 2016, Minnesota had a 20 percent increase over 2015 in opioid-related deaths. Hennepin County alone saw a 36 percent increase. To fully understand the rising rates of death, overdose and abuse, it's important to know some facts about opioids and opioid manufacturers. • In 1991, doctors prescribed 76 million opioids. In 2012, that number exploded to 259 million. • Since 1999, more than 200,000 Americans have died from overdoses involving opioid painkillers.